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Reprogramming bacterial protein organelles as a nanoreactor for hydrogen production.
Li T, Jiang Q, Huang J, Aitchison CM, Huang F, Yang M, Dykes GF, He HL, Wang Q, Sprick RS, Cooper AI, Lu-Ning Liu*
Nature Communications, 2020, in press, DOI: 10.1038/s41467-020-19280-0.

Membrane dynamics in phototrophic bacteria.
Mullineaux CW*, Lu-Ning Liu*
Annual Review of Microbiology, 2020, 74: 633-654. DOI: 10.1146/annurev-micro-020518-120134. [fulltext]

mRNA localisation, reaction centre biogenesis and thylakoid membrane targeting in cyanobacteria.
Mahbub M, Hemm L, Yang Y, Kaur R, Carmen H, Engl C, Huokko T, Riediger M, Watanabe S, Lu-Ning Liu, Wilde A, Hess W, Mullineaux CW
Nature Plants, 2020, 6(9), 1179-1191. DOI: 10.1038/s41477-020-00764-2. [fulltext]

Structural variability, coordination, and adaptation of a native photosynthetic machinery.
Zhao LS, Huokko T, Wilson S, Simpson DM, Wang Q, Ruban AV, Mullineaux CW, Zhang YZ*, Lu-Ning Liu*
Nature Plants, 2020, 6(7): 869-882. DOI: 10.1038/s41477-020-0694-3. [fulltext]
Recommended in Faculty Opioions:
Featured in Media: EurekAlert!,, Nature Microbiology Community, University News, Weichat (cn).

Decoding the stoichiometric composition and organisation of bacterial metabolosomes.
Yang M, Simpson DM, Wenner N, Brownridge P, Harman VM, Hinton JCD, Beynon RJ, Lu-Ning Liu*
Nature Communications, 2020, 11(1): 1976. DOI: 10.1038/s41467-020-15888-4. [fulltext]
Featured in Media: University News, Weichat (cn).

Rubisco accumulation factor 1 (Raf1) plays essential roles in mediating Rubisco assembly and carboxysome biogenesis.
Huang F, Kong W, Sun Y, Chen T, Dykes GF, Jiang YL, Lu-Ning Liu*
Proc Natl Acad Sci USA, 2020, 117(29): 17418-17428. DOI: 10.1073/pnas.2007990117. [fulltext]
Featured in Media: EurekAlert!, University News, Weichat (cn).

Unfolding pathway and intermolecular interactions of the cytochrome subunit in the bacterial photosynthetic reaction center.
Leanne C. Miller, Longsheng Zhao, Daniel P. Canniffe, David Martin, Lu-Ning Liu*
Biochim Biophys Acta - Bioenergetics, 2020, 1861(8): 148204, DOI: 10.1016/j.bbabio.2020.148204. [fulltext]
Featured in Media: University News.

Photosynthesis in phytoplankton: Insights from the newly discovered biological inorganic carbon pumps.
Na Sui#, Fang Huang#,*, Lu-Ning Liu*
Molecular Plant, 2020, 13(7): 949-951. DOI: 10.1016/j.molp.2020.05.003. [fulltext]

Diurnal regulation of in vivo localization and CO2-fixing activity of carboxysomes in Synechococcus elongatus PCC 7942.
Yaqi Sun, Fang Huang, Gregory Dykes, Lu-Ning Liu*
Life, 2020, 10(9), 169, DOI: 10.3390/life10090169. [fulltext]

Structural visualization of septum formation in Staphylococcus warneri using atomic force microscopy.
Hai-Nan Su, Kang Li, Xiao-Xue Yuan, Meng-Yao Zhang, Si-Min Liu, Xiu-Lan Chen,Lu-Ning Liu*, Yu-Zhong Zhang*
Journal of Bacteriology, 2020, 202(19): e00294-20. DOI: 10.1128/JB.00294-20. [fulltext] (cover article)

Molecular simulations unravel the molecular principles that mediate selective permeability of carboxysome shell protein.
Faulkner M, Szabo I, Weetman SL, Sicard F, Huber HG, Bond PJ, Rosta E*, Lu-Ning Liu*
Scientific Reports, 2020, 10: 17501. DOI: 10.1038/s41598-020-74536-5. [fulltext]

Altered N-glycan composition impacts flagella mediated adhesion in Chlamydomonas reinhardtii.
Hippler M, Xu N, Oltmanns A, Zhao L-S, Girot A, Karimi M, Hoepfner L, Kelterborn S, Scholz M, Beißel J, Hegemann P, Bäumchen O, Liu LN, Huang K
bioRxiv, 2020, DOI: [fulltext]

Self-assembly, organisation, regulation, and engineering of carboxysomes: CO2-fixing prokaryotic organelles.
Sun Y, Huang F, Lu-Ning Liu*
Microbial Photosynthesis. Springer Nature, edited by Q Wang, 2020, 319-343. DOI: 10.1007/978-981-15-3110-1_15.

Composition, organisation, and function of purple photosynthetic machinery.
Miller LC, Martin DS, Lu-Ning Liu, Canniffe DP*
Microbial Photosynthesis. Springer Nature, edited by Q Wang, 2020, 73-114. DOI: 10.1007/978-981-15-3110-1_4.

The roles of chloroplast membrane lipids in abiotic stress responses
Jinlu Li, Lu-Ning Liu, Qingwei Meng, Hai Fan, Na Sui
Plant Signaling & Behavior, 2020, 1807152. DOI: 10.1080/15592324.2020.1807152. [fulltext]

Responses of membranes and the photosynthetic apparatus to salt stress in cyanobacteria.
Wenjing Yang, Fang Wang, Lu-Ning Liu, Na Sui*
Frontiers in Plant Science, 2020, 11: 713. DOI: 10.3389/fpls.2020.00713. [fulltext]

Comparative transcriptome analysis reveals new lncRNAs responding to salt stress in sweet sorghum.
Xi Sun, Hongxiang Zheng, Jinlu Li, Lu-Ning Liu, Xiansheng Zhang*, Na Sui*
Frontiers in Bioengineering and Biotechnology, 2020, 8: 331. DOI: 10.3389/fbioe.2020.00331. [fulltext]

Photosynthetic regulation under salt stress and salt-tolerance mechanism of sweet sorghum.
Yang Z, Li JL, Lu-Ning Liu, Xie Q, Sui N*
Frontiers in Plant Science, 2020, 10: 1722. DOI: 10.3389/fpls.2019.01722. [fulltext]

Structural mechanism of the active bicarbonate transporter from cyanobacteria.
Wang C, Sun B, Zhang X, Huang X, Zhang M, Guo H, Chen X, Huang F, Chen T, Mi H, Yu F, Liu LN, Zhang P*.
Nature Plants, 2019, 5(11): 1184-1193. DOIi:10.1038/s41477-019-0538-1. [fulltext]
Featured in Media: University News,

Cryo-electron microscopy delineates the in situ structure of the thylakoid network.
Liu LN*, Zhang YZ
Molecular Plant, 2019, 12(9): 1176-1178. DOI: [fulltext]

Single-organelle quantification reveals the stoichiometric and structural variability of carboxysomes dependent on the environment.
Sun Y, Wollman A, Huang F, Leake MC, Liu LN*
Plant Cell, 2019, 31(7): 1648-1664; DOI: [fulltext]
BioRxiv, 2019, 568238. DOI: [fulltext]
Featured in Media: University News, Weixin (cn).

Self-assembly stability and variability of bacterial microcompartment shell proteins in response to the environmental change.
Faulkner M, Zhao LS, Barrett S, Liu LN*
Nanoscale Research Letters, 2019, 14:54. DOI: 10.1186/s11671-019-2884-3. [fulltext]

Phycobiliproteins: Molecular Structure, Production, Applications, and Prospects.
Li W, Su HN, Pu Y, Chen J, Liu LN, Liu Q, Qin S.
Biotechnology Advances, 2019, 37: 340-353. DOI: 10.1016/j.biotechadv.2019.01.008. [fulltext]

Roles of RbcX in carboxysome biosynthesis in the cyanobacterium Synechococcus elongatus PCC7942.
Huang F, Vasieva O, Sun Y, Faulkner M, Dykes G, Zhao Z, Liu LN*.
Plant Physiology, 2019, 179(1): 184-194. DOI: 10.1104/pp.18.01217. [fulltext]
Featured in Media: University News, Weixin (cn), Plantae.

Nanoscale visualization of bacterial microcompartments using atomic force microscopy.
Rodriguez-Ramos J, Faulkner M, Liu LN*.
Methods in Molecular Biology, 2018, 1814: 373-383. DOI:10.1007/978-1-4939-8591-3_22. [fulltext]

Engineering and modulating functional cyanobacterial CO2-fixing organelles.
Fang Y, Huang F, Faulkner M, Jiang Q, Dykes GF, Yang M, Liu LN*.
Frontiers in Plant Science, 2018, 9: 739. DOI:10.3389/fpls.2018.00739. [fulltext]

Insights into the origin of distinct medin fibril morphologies induced by incubation conditions and seeding.
Davies HA, Lee CF, Miller L, Liu LN, Madine J.
International Journal of Molecular Sciences, 2018, 19(5): 1357. DOI:10.3390/ijms19051357. [fulltext]

Dissecting the native architecture and dynamics of cyanobacterial photosynthetic machinery.
Casella S, Huang F, Mason D, Zhao GY, John GN, Mullineaux CW, Liu LN*.
Molecular Plant, 2017, 10(11): 1434–1448. DOI: 10.1016/j.molp.2017.09.019.(cover article)[fulltext]
Featured in Media: University News, Weixin (cn).

Direct characterization of the native structure and mechanics of cyanobacterial carboxysomes.
Faulkner M, Rodriguez-Ramos J, Dykes GF, Owen SV, Casella S, Simpson DM, Beynon RJ, Liu LN*.
Nanoscale, 2017, 9(30): 10662-10673, DOI:10.1039/C7NR02524F. [fulltext]
Featured in Media: ScienceDaily, ScienceNewsLine, Nano Magazine,, EurekAlert!, University News.

Supramolecular architecture of photosynthetic membrane in red algae in response to nitrogen starvation.
Zhao LS, Su HN, Li K, Xie BB, Liu LN, Zhang XY, Chen XL, Huang F, Zhou BC, Zhang YZ.
Biochim Biophys Acta–Bioenergetics, 2016, 1857(1): 1751–1758. DOI:10.1016/j.bbabio.2016.08.005. [fulltext]

Light modulates the biosynthesis and organization of cyanobacterial carbon fixation machinery through photosynthetic electron flow.
Sun Y, Casella S, Fang Y, Huang F, Faulkner M, Barrett S, Liu LN*.
Plant Physiology, 2016, 171(1): 530-541. DOI:10.1104/pp.16.00107. [fulltext]
Featured in Media: ScienceDaily, ScienceNewsLine, NanoWerk,, SpectroscopyNow, University News. (#5 of the most attention-getting articles in Plant Physiology during the YEAR 2018: Twitter)

Visualization of bacterial microcompartment facet assembly using high-speed atomic force microscopy.
Sutter M, Faulkner M, Aussignargues C, Paasch BC, Barrett S, Kerfeld CA, Liu LN*.
Nano Letters, 2016, 16(3): 1590-1595, DOI: 10.1021/acs.nanolett.5b04259. (correspondence, cover article)[fulltext]
Featured in Media:, WeeklyHotNews, TJS Kitchen Appliances, University News.

Distribution and dynamics of electron transport complexes in cyanobacterial thylakoid membranes.
Liu LN*.
Biochim Biophys Acta - Bioenergetics, 2016, 1857(3): 256-265. DOI: 10.1016/j.bbabio.2015.11.010. (cover article)[fulltext]

Revised genome sequence of the purple photosynthetic bacterium Blastochloris viridis.
Liu LN*, Faulkner M, Liu X, Huang F, Darby AC, Hall N.
Genome Announcements, 2016, 4(1): e01520-15. DOI:10.1128/genomeA.01520-15. (correspondence)[PDF]

Adaptation and regulation of photosynthetic apparatus in response to light.
Casella S, Huang F, Liu LN.
Handbook of Photosynthesis, Third Edition.
CRC Press, US, edited by Mohammad Pessarakli. 2016, 53-63.

Oxidative stress alters morphology and toxicity of aortic medial amyloid.
Davies HA, Phelan MM, Wilkinson MC, Migrino RQ, Truran S, Franco DA, Liu LN, Longmore CJ, Madine J.
Biophys J, 2015, 109(11): 2363-2370. [PDF]

CLL exosomes modulate the transcriptome and behaviour of recipient stromal cells and are selectively enriched in miR-202-3p.
Farahani M, Rubbi C, Liu LN, Slupsky JR, Kalakonda N.
PLoS ONE, 2015, 10(10): e0141429. [PDF]

Localisation and interactions of the Vipp1 protein in cyanobacteria.
Bryan SJ, Burroughs NJ, Shevela D, Yu J, Rupprecht E, Liu LN, Mastroianni G, Xue Q, Llorente-Garcia I, Leake MC, Eichacker LA, Schneider D, Nixon PJ, Mullineaux CW.
Mol Microbiol, 2014, 94(5): 1179-1195. [PDF]

Phycobilisome mobility and its role in regulation of light-harvesting in red algae.
Kana R, Kotabova E, Lukes M, Papacek S, Matonoha C, Liu LN, Prasil O, Mullineaux CW.
Plant Physiol, 2014, 165(4): 1618-1631. [PDF]

The architecture of Rhodobacter sphaeroides chromatophores.
Scheuring S, Nevo R, Liu LN, Mangenot S, Charuvi D, Boudier T, Prima V, Hubert P, Sturgis JN, Reich Z.
Biochim Biophys Acta - Bioenergetics, 2014, 1837(8): 1263-1270. [PDF]

Single-molecule in vivo imaging of bacterial respiratory complexes indicates delocalized oxidative phosphorylation.
Llortente-Garcia I, Lenn T, Erhardt H, Harriman O, Liu LN, Robson A, Chiu SW, Matthews S, Willis N, Bray C, Lee SH, Shin JY, Bustamante C, Liphardt J, Friedrich T, Mullineaux C, Leake M.
Biochim Biophys Acta - Bioenergetics
, 2014, 1837(6): 811-824. [PDF]

Delocalised electron transport and chemiosmosis in Escherichia coli.
Mullineaux CW, Lenn T, Llortente-Garcia I, Erhardt H, Harriman O, Liu LN, Friedrich T, Leake M.
Biochim Biophys Acta - Bioenergetics
, 2014, 1837: e88, DOI: 10.1016/j.bbabio.2014.05.100. [Fulltext]

Investigation of photosynthetic membrane structure using atomic force microscopy.
Liu LN*, Scheuring S.
Trends Plant Sci
, 2013, 18(5): 277-286. (correspondence, featured article) [PDF]

Control of electron transport routes through redox-regulated redistribution of respiratory complexes.
Liu LN*, Bryan SJ, Huang F, Yu JF, Nixon PJ, Rich PR, Mullineaux CW.
Proc Natl Acad Sci USA, 2012, 109 (28): 11431-11436. (*correspondence) [PDF]
Featured in media: ScienceDaily and ScienceNewsline: Biological Switch Paves Way for Improved Biofuel Production; RenewableEnergyWorld and EcoMagination: Illuminated Bacteria Enlighten Biofuel Production.

High-resolution AFM imaging of native biological membranes.
Liu LN, Scheuring S.
Nanoscale Liquid Interfaces: Wetting, Patterning and Force Microscopy at Molecular Scale. Pan Stanford Publishing, Singapore, edited by T. Ondarçuhu and J.-P. Aimé. 2012, 655-678. [PDF]

Forces guiding assembly of light-harvesting complex 2 in native membranes.
Liu LN, Duquesne K, Oesterhelt F, Sturgis JN, Scheuring S.
Proc Natl Acad Sci USA
, 2011, 108 (23): 9455-9459. [PDF]

Native architecture of the photosynthetic membrane from Rhodobacter veldkampii.
Liu LN
, Sturgis JN, Scheuring S.
J Struct Biol
, 2011, 173 (1): 138-145. [PDF]

High resolution imaging and manipulation of membrane proteins.
Buzhynskyy N, Liu LN, Casuso I, Scheuring S.
Life at the Nanoscale: Atomic Force Microscopy of Live Cells. Pan Stanford Publishing, Singapore, edited by Y.F. Dufrene. 2011, 21-44. [PDF]

Quinone pathways in entire photosynthetic chromatophores of Rhodospirillum photometricum.
Liu LN, Duquesne K, Sturgis JN, Scheuring S.
J Mol Biol, 2009, 393 (1): 27-35. [PDF]

FRAP analysis on red alga reveals the fluorescence recovery is ascribed to intrinsic photoprocesses of phycobilisomes than large-scale diffusion.
Liu LN
, Aartsma TJ, Thomas JC, Zhou BC, Zhang YZ.
, 2009, 4(4): e5295. doi:10.1371/journal.pone.0005295. [PDF]

Probing the pH sensitivity of R-phycoerythrin: Investigations of active conformational and functional variation.
Liu LN#, Su HN#, Yan SG, Shao SM, Xie BB, Chen XL, Zhang XY, Zhou BC, Zhang YZ.
Biochim Biophys Acta - Bioenergetics, 2009, 1787 (7): 939–946. [PDF]

Watching the native supramolecular architecture of photosynthetic membrane in red algae: Topography of phycobilisomes, and their crowding, diverse distribution patterns.
Liu LN, Aartsma TJ, Thomas JC, Lamers GEB, Zhou BC, Zhang YZ.
J Biol Chem
, 2008, 283 (50): 34946-34953. (cover article) [PDF]

Dimers of light-harvesting complex 2 from Rhodobacter sphaeroides characterized in reconstituted 2D crystals with atomic force microscopy.
Liu LN, Aartsma TJ, Frese RN.
, 2008, 275 (12): 3157-3166. (cover article) [PDF]

Light-induced energetic decoupling as a mechanism for phycobilisome-related energy dissipation in red algae: a single molecule study.
Liu LN, Elmalk AT, Aartsma TJ, Thomas JC, Lamers GEB, Zhou BC, Zhang YZ.
PLoS ONE, 2008, 3(9): e3134. doi:10.1371/journal.pone.0003134. [PDF]

Structure and organization of phycobilisomes on membranes of the red alga Porphyridium cruentum.
Arteni AA#, Liu LN#, Ajlani G, Aartsma TJ, Zhang YZ, Zhou BC, Boekema EJ.
Photosynth Res
, 2008, 95 (2-3): 169-174. (#co-first author) [PDF]

Characterization, structure and function of linker polypeptides in phycobilisome of cyanobacteria and red algae: an overview.
Liu LN, Chen XL, Zhang YZ, Zhou BC.
Biochim Biophys Acta - Bioenergetics
, 2005, 1708 (2): 133-142. [PDF]

One-step chromatography method for efficient separation and purification of R-phycoerythrin from Polysiphonia urceolata.
Liu LN, Chen XL, Zhang XY, Zhang YZ, Zhou BC.
J Biotechnol, 2005, 116 (1): 91-100. [PDF]

Factors that effect antioxidant activity of C-phycocyanins from Spirulina platensis.
Zhou ZP, Liu LN, Chen XL, Zhang YZ, Zhou BC.
J Food Biochem, 2005, 29: 313–322. [PDF]

Effects of light, denaturants and pH on antioxidant activity of allophycocyanin in Spirulina platensis.
Zhou ZP, Liu LN, Chen XL, Zhang XY, Zhang YZ, Zhou BC.
Oceanologia et Limnologia Sinica
, 2005, 36 (2): 179-185. 

Effects of hirudin for the thrombin-induced expression of adhesive molecules in neutrophils and human umbilical vein endothelial cells.
Wang M, Cui LQ, Wang XJ, Han QX, Liu LN.
Chinese J New Drugs, 2005, 14(8): 989-992.

The study on the factors influencing the stability of the phycocyanin in Spirulina liquor.
Liu LN, Huang F, Huang YL.
Liquor Making, 2004, 31(3): 43-45

Effect of CHAPS on the stability of Spirulina platensis phycobilisomes.
Zhang XY, Liu LN, Chen XL, Zhang YZ, Zhou BC.
Spectroscopy and Spectral Analysis
, 2004, 24: 1224-1226.

The study of the stability of phycobilisomes in algae, Spirulina platensis.
Zhang XY, Liu LN, Chen XL, Zhang YZ, Zhou BC.
Marine Science, 2004, 28: 38-42.


Invited talks

2019 Bruker Scanning Probe Microscope conference, Liverpool, UK, December 4, 2019.

Cotton Research Center, Shandong Academy of Agricultural Sciences, Jinan, China, April 22, 2019.

College of Life Sciences, Shanghai Normal University, Shanghai, China, April 16, 2019.

School of Life Sciences, University of Science and Technology of China, April 14, 2019.

Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China, April 12, 2019.

National Key Laboratory of Crop Genetic Improvement and National Centre of Plant Gene Research, Huazhong Agricultural University, Wuhan, China, April 11, 2019.

Annual Conference of the Association for General and Applied Microbiology, March 17-20, 2019, Mainz, Germany

1st Asia-Oceania International Congress on Photosynthesis, August 19-23, 2018, Beijing, China

1st European Conference for Photosynthesis Research, June 25-28, 2018, Uppsala, Sweden

10th European Workshop on the Molecular Biology of Cyanobacteria, Clui-Napoca, Romania

Self-assembly dynamics and functional regulation of bacterial microcompartments. The 9th International Symposium on Inorganic Carbon Utilization by Aquatic Photosynthetic Organisms, Cambridge, UK, 15 August, 2016.

Light modulates the biosynthesis and organization of cyanobacterial carbon fixation machinery. The 17th International Congress on Photosynthesis Research, Maastricht, Netherlands, 10 August, 2016.

Probing self-assembly of bacterial microcompartments using high-speed atomic force microscopy. British Biophysical Society 2016 Biennial Meeting, Liverpool, UK, 7 July, 2016.

Supramolecular organisation and adaptation of photosynthetic machinery. Shanghai Institutes for Biological Sciences, Chinese Academy of Science, Shanghai, China, 9 May, 2013.

Unravelling the supramolecular organisation and interactions of the native photosynthetic apparatus by AFM. Université de Lorraine, Nancy, France, 5-7 Nov, 2012.

Control of electron transport routes through redox-regulated redistribution of respiratory complexes.
17th European Bioenergetics Conference, Freiburg, Germany, 15-20 September, 2012.

Control of electron transfer routes through redistribution of respiratory complexes.
Biochemical Society Christmas Bioenergetics Meeting, Imperial College London, UK, 16th December 2011.

Supramolecular architecture, assembly and dynamics of native photosynthetic membranes.
School of Life Sciences, University of Science and Technology of China, November 2011.

The in vivo localisation of NDH-1 complexes in cyanobacteria.
Molecular Bioenergetics of Cyanobacteria: From Cell to Community, Spain, April 2011.

High-resolution AFM of the bacterial photosynthetic apparatus.
The 12th International Scanning Probe Microscopy Conference, Sapporo, Japan, May 2010.

The architecture and organization of phycobilisomes on the photosynthetic membrane in red algae using atomic force microscopy.Gordon Research Conference on Photosynthesis, Smithfield, US, August 2009.