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Welcome to the Liu Lab

Self-assembly and defined biosynthesis are extraordinary biological processes to govern and modulate cell physiology. By applying and developing multidisciplinary techniques, including molecular genetics, biochemistry, synthetic biology and biophysical approaches, the Liu Lab aims to uncover the molecular principles driving the self-assembly and maintenance of protein complexes and metabolic machines. Our study will inform rational design and engineering of proteins, enzymes, membranes, new bioinspired nanomaterials, bionanoreactors, and cages for varous biotechnological and biomedical applications, to make our life better and green in a sustainable manner.

Research Expertise
Biochemistry, Molecular Biology, Microbiology, Structural Biology, Biophysics, Nanotechnology, Synthetic Biology

Current Projects
- Compartmentalisation, self-assembly, and synthetic engineering of bacterial microcompartments
- Biogenesis and regulation of photosynthetic machinery
- Structure and formation of biological membranes and protein machines

Methodologies
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Molecular genetics, biochemistry, synthetic biology
- Genomics, proteomics and metabolomics
- High-resolution microscopy, including atomic force microscopy, (cryo-)electron microscopy, confocal/TIRF microscopy
- Optical spectroscopy including absorption, fluorescence and circular dichroism spectroscopy

 

Selected Publications (Full publication list)

News


Fundings

RS BBSRC

MC CN