Inhibitors and Drugs

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Name	Location	Supplier	Catalogue number	Target / Effect
LRRK2-IN-1	freezer in front of the lab (2nd drawer, from bottom) 23/10/14, 10mM in DMSO	D. Alessi/Merck	438193	LRRK2
GNE-0877	Leila's box -80°C (aliquots) 16/09/15, 10mM in DMSO	Selleckem	S7367
GSK2578215A	Leila's box -80°C (aliquots) 22/02/16, 10mM in DMSO use at 500nM final	Selleckem	S7664
LRRK2 Inhibitor III, HG-10-102-01	Leila's box -20°C (aliquots) 22/02/16, 10mM in DMSO use at 500nM final	Merck Millipore	438195
Rapamycin	Leila's box -80°C (aliquots) 10/09/15, 10mM in DMSO use at 1µM final	Selleckem	S1039	MTOR (increases pigmentation)
PTU (N-Phenylthiourea)	Leila's bench (powder) 10/09/15, 200mM in EtOH -20°C (eppendorfs) use at 200µM final	SIGMA	103-85-5	Tyrosinase (decreases pigmentation
L-Dopa/ 3,4-Dihydroxy-L-phenylalanine	Leila's bench (powder)	SIGMA	D 9628	Tyrosinase substrate (melanin precursor)
CCCP	freezer 2, -20°C (aliquots) 100mM in DMSO use at 10µM final			Protonophore
Deferiprone/ DFP/ 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone	Leila's bench (powder) 5mM (in Water) fresh solution heat at 95°C, sterile filtered use at 1mM final	SIGMA	379409	Iron chelator
Phos-tag™	Powder stock (2mg) Fride n°3, drawer n°6 21/12/16 Solution in a sterilin 5mM Phos-tagTM AAL Solution containing 3% (v/v) MeOH Fridge n°1, drawer n°3	Alphalabs (Wako Nard Institute)	300-93523	Acrylamide AAL-107 phosphate tag phosphate-affinity SDS-PAGE electrophoresis
Phorbol 12-myristate 13-acetate (TPA)	Leila's box -80°C (aliquots) 25/07/16 2mM in pure EtOH and 40uM in PBS 1% serum use at 200nM final	SIGMA	P8139	Potent tumor promoter activates protein kinase C