 |
Final Programme (updated
17th Feb. 2006)
Conference programme for Tuesday 18th April
| 11:00 - 18:00 |
Delegate arrival and registration |
| 13:00 |
Opening Ceremony |
| |
Welcome by J Caldwell
Dean of The Faculty of Medicine,
The University of Liverpool |
| |
Welcome by BK Park
Congress Chairperson,
Head of Pharmacology, The University of Liverpool |
Perspectives
on Drug Hypersensitivity (Chair: Caldwell & Ikezawa) |
| 13:30 |
Drug industry perspective (T Kawabata, USA) |
| 14:10 |
Clinical perspective (P Friedmann, UK) |
| 14:50 |
Regulatory perspective (AM Breckenridge, MHRA, UK) |
| 15:30 |
Refreshments |
Symposium 1 : Clinical
Aspects of Drug Hypersensitivity (Chair: Demoly & Khan) |
| 16:00 |
Clinical manifestation of drug hypersensitivity (A Bircher, CH)
|
| 16:40 |
Drug allergy work-up: ENDA/EAACI recommendations (P Demoly, France)
|
| 17:20 |
Management of patients with drug hypersensitivity (W Aberer, Austria)
|
18:00
18.40 |
Lessons from the French registry on anaphylaxis during general
anaesthesia (M Mertes, France)
WONDA (P Demoly, France, W Pichler) |
| 19:00 - 21:00 |
Welcome Reception |
Conference programme for Wednesday 19th April
| 08:30 - 12:00 |
Registration desk Open |
| Symposium 2: Mechanisms of Chemical Allergy
(Chair: Pease & Naisbitt) |
| 09:00 |
Interaction of low molecular weight chemicals with protein (C
Pease, UK) |
| 09:40 |
Dendritic cell mobilisation following exposure to chemical allergens (I, Kimber, UK) |
| 10:20 |
Coffee |
| 10:40 |
Stimulation of T-cells following exposure to chemical allergens (S Martin, Germany) |
| 11:20 |
Role of regulatory T-cells in chemical allergy (A Cavani, Italy) |
12:00
|
Selected oral communications
1. Skin sensitising potentials of dinitrochlorobenzene (DNCB) and dinitrothiocyanobenzene (DNTB) in humans.C Pickard, A Smith, C McGuire, HL Cooper, JM Jackson, M Bradley, RJ Dearman, M Cumberbatch, I Kimber, PS Friedmann (UK).
2. Comparative proteomic analysis of metal-protein interactions in human antigen presenting cells (APC). C Junkes, S Helm, S Eikelmeier, N Guerreiro, HU Weltzien, H-J Thierse (Germany / Switzerland).
3. Diagnostic use of IL- 6 release by peripheral blood mononuclear cells from patients with different Clinical forms of drug hypersensitivity. J Baló-Banga Mathias, K Schweitzer, I Eördögh, J Fûrész (Hungary). |
| 12:45 |
Lunch |
Symposium 3: Epidemiology
of Drug Hypersensitivity (Chair: Shear & Roujeau) |
| 13:45 |
Epidemiology of drug hypersensitivity (N Shear, Canada) |
| 14:25 |
Lessons from the SCAR European Registry (JC Roujeau, France) |
| 15:05 |
Tea |
| 15:35 |
Epidemiology and pathogenesis of anaphylaxis (R Pumphrey, UK) |
| 16:15 |
Perspectives on drug induced immune liver injury (G Kenna, UK) |
| 18:00-19.00 |
Posters and wine reception |
Conference Programme for Thursday 20th April
| 08:30 - 12:00 |
Registration desk open |
Symposium 4: Chemical
and Cellular Basis of Drug Hypersensitivity (Chair: Park &
Uetrecht) |
| 09:00 |
The relationship between metabolic activation and drug sensitivity (J Uetrecht, Canada) |
| 09:40 |
Stimulation of immune cells by chemically inert drugs (W Pichler, Switzerland) |
| 10:20 |
Coffee |
| 10:40 |
Evaluation of the effects of drugs on co-stimulatory receptor expression (R Pieters, The Netherlands) |
| 11:20 |
Relationhip between viral reactivation and drug hypersensitivity (T Shiohara, Japan) |
12:00
|
Selected oral communications
1. Agonism, partial agonism and antagonism of sulfanilamides on sulfamethoxazole-specific T cell receptors. BO Gerber, JPH Depta, DA Schmid, WJ Pichler (Switzerland).
2. Human T cell responses to phenytoin require metabolism-dependent processing and presentation. HL Cooper, C Pickard, E Healy, PS Friedmann (England).
3. A study of the sequence of events involved in nevirapine-induce skin rash in brown norway rats. M Popovic, J Caswell, JP Uetrecht (Canada). |
| 12:45 |
Lunch |
Symposium 5: Immunogenetics
of Drug Hypersensitivity (Chair: Pirmohamed & Mallal) |
| 13:45 |
Recent advances in pharmaco- and immunogenetics (M Pirmohamed, UK) |
| 14:25 |
Predisposition to drug hypersensitivity in patients with HIV (S
Mallal, Australia) |
| 15:05 |
Tea |
| 15:35 |
Predisposition to severe cutaneous drug hypersensitivity reactions (Y Chen, Taiwan) |
16:15
|
Selected oral communications
1. Severe Cutaneous Drug Hypersensitivity and Herpes Virus Infection. Z Ikezawa, Ch Watanabe, K Nakamura, N Mitani, M Aihara (Japan).
2. Abacavir Patch Testing and Rechallenge in Patients Labeled with Abacavir Hypersensitivity Syndrome. EJ Phillips, G Larsen, Z Brumme, M Harris, J Toy, R Harrigan, S Mallal, JSG Montaner (Canada/Australia).
3. Animal Models of Toxic Epidermal Necrolysis. H Azukizawa , H Kosaka, S Sano, S Itami, I Katayama (Japan). |
| 18:00 |
Congress Dinner (Crowne Plaza, Liverpool) |
Conference Programme for Friday 21st April
| 08:30 - 12:00 |
Registration desk open |
Symposium 6: Laboratory
Investigations into the Fundamental Mechanisms of Drug Hypersensitivity
(Chair: Pichler & Weltzien) |
| 09:00 |
Presentation of low molecular weight chemicals to T-cells (H Weltzien,
Germany) |
| 09:40 |
Specificity and sensitivity of T-cell recognition (A. George,
UK) |
| 10:20 |
Coffee |
| 10:40 |
IgE mediated drug hypersensitivity: from in vitro models to clinical
benefit (M Castells, USA) |
| 11:20 |
Relationship between localised metabolic activation of drugs and immune cell activation (D Naisbitt, UK) |
| 12:00 |
Selected oral communications
1. Dendritic Cell Metabolism of Sulfamethoxazole Leads to Increased CD40 Expression. JP Sanderson, DJ Naisbitt, J Farrell, N Drummond, K Mathews, M Pirmohamed, SE Clarke, BK Park (England).
2. Protein haptenation in dendritic cells exposed to sulfonamide or sulfone. S Roychowdhury, CK Svensson (USA).
3. T cell responses to CTACK/CCL27 and TARC/CCL17 in drug hypersensitivity reactions: implications in cytotoxic T cell recruitment to skin. B Tapia, E Morel, MÁ Martín-Díaz, R Díaz, A Padial, T Bellón (Spain). |
| 12:45 |
Lunch |
Symposium 7: Individual
Susceptible to Drug Hypersensitivity (Chair: Rieder & Khan) |
| 13:45 |
Drug hypersensitivity in children (M Rieder, Canada) |
| 14:25 |
Drug hypersensitivity in HIV (JC Roujeau, France) |
| 15:05 |
Tea |
| 15:35 |
Current thoughts on rechallenge (A Romano, Italy) |
| 16:15 |
Closing Ceremony |
|
|
