Publications
Chen C, Duckworth CA, Fu B, Pritchard DM, Rhodes JM, Yu LG. Circulating galectins -2, -4 and -8 in cancer patients make important contributions to the increased circulation of several cytokines and chemokines that promote angiogenesis and metastasis Br J Cancer (2014) vol 110 issue 3 pp 741-52
Williams JM, Duckworth CA, Watson AJ, Frey MR, Miguel JC, Burkitt MD, Sutton R, Hughes KR, Hall LJ, Caamano JH, Campbell BJ, Pritchard DM.A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide. Disease Models & Mechanisms (2013) vol 6 issue 6 pp 1388-99
Burkitt MD, Williams JM, Duckworth CA, O'Hara A, Hanedi A, Varro A, Caamano JH, Pritchard DM. Signaling mediated by the NF-kB sub-units NF-kB1, NF-kB2 and c-Rel differentially regulate Helicobacter felis-induced gastric carcinogenesis in C57BL/6 mice. Oncogene (2013) vol 32 issue 50 pp 5563-73
Duckworth CA, Clyde D, Worthley DL, Wang TC, Varro A, Pritchard DM. Progastrin-induced secretion of IGF-II from colonic myofibroblasts stimulates colonic epithelial proliferation. Gastroenterology (2013) vol 145 pp 197-208
Barrow H*, Tam B*, Duckworth CA*, Rhodes JM, Yu LG. Suppression of Core 1 Gal-transferase is associated with reduction of TF and reciprocal increase of Tn, sialyl-Tn and Core 3 glycans in human colon cancer cells. PLoS One (2013) vol 8 pp e59792 *Authors share first authorship
Chen C, Duckworth CA, Zhao Q, Pritchard DM, Rhodes JM, Yu LG. Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium. Clin Cancer Res (2013) in press
Duckworth CA, Yu LG. Galectins in the blood circulation: potential therapeutic targets of cancer metastasis. ACS Symposium Series (2012) vol 1115 Chapter 18 pp309-322
Duckworth CA, Clyde D, Pritchard DM. CD24 is expressed in gastric parietal cells and regulates apoptosis and the response to Helicobacter felis infection in the murine stomach. A J Physiol Gastrointest Liver Physiol (2012) vol 303 pp G915-26
Kiesslich R*, Duckworth CA*, Moussata D, Gloeckner A, Lim LG, Goetz M, Galle PR, Neurath MF, Watson AJM. Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease. Gut (2012) vol 61 pp 1146-53 *Both authors share first authorship
Duckworth CA, Watson AJ. Analysis of epithelial cell shedding and gaps in the intestinal epithelium. Meth Mol Biol (2011) vol 763 pp 105-14
Marchiando AM, Shen L, Graham WV, Edelblum KL, Duckworth CA, Guan Y, Montrose MH, Turner JR, Watson AJ. The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. Gastroenterology (2011) vol 140 issue 4 pp 1208-1218
Duckworth CA. Understanding gene-environment interactions in a mouse model of Crohn's disease. Disease Models & Mechanisms (2011) vol 4 issue 1 pp 7-8
Watson AJ, Duckworth CA. Gut microbiota control gut permeability through GLP-2. Gastroenterology (2010) vol 138 issue 2 pp 779-81
Duckworth CA, Pritchard DM. Suppression of apoptosis, crypt hyperplasia, and altered differentiation in the colonic epithelia of bak-null mice. Gastroenterology (2009) vol 136 issue 3 pp 943-52
Watson AJ, Duckworth CA, Guan Y, Montrose MH. Mechanisms of epithelial cell shedding in the mammalian intestine and maintenance of barrier function. Ann N Y Acad Sci (2009) vol 1165 pp 135-42
Przemeck SM, Duckworth CA, Pritchard DM. Radiation-induced gastric epithelial apoptosis occurs in the proliferative zone and is regulated by p53, bak, bax, and bcl-2. Am J Physiol Gastrointest Liver Physiol (2007) vol 292 issue 2 pp 620-7
Ottewell PD, Duckworth CA, Varro A, Dimaline R, Wang TC, Watson AJ, Dockray GJ, Pritchard DM. Gastrin increases murine intestinal crypt regeneration following injury. Gastroenterology (2006) vol 130 issue 4 pp 1169-80