Research activities at the DSMZ – More than just a collection


Johannes Wittmann, Julia Sabirova, Imke Schmidt, Christine Rohde

Leibniz Institute DSMZ – German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany


It is a mission of culture collections like the Leibniz Institute DSMZ to conserve microbial resources for the scientific community and for future generations, to keep them safe and secure, authentic and viable. The DSMZ is a governmentally supported non-profit institution of the German public services and performs front-line basic and applied research. Since more than 25 years, the DSMZ is experienced in handling phages and holds currently more than 350 purified titre-controlled phage isolates in liquid nitrogen stocks and vacuum-dried. This collection continuously expands: researchers are encouraged to deposit phages in the open DSMZ collection, deposit is free of any costs, or to become member of the Phage Trapper project. Our scientific phage studies are aiming at a deeper understanding of phage biology and benefit from the rich pool of bacterial strains available at the own collection and from excellent international networking activities, e.g. with the George Eliava Institute IBMV, Tbilisi and with P.H.A.G.E. The DSMZ research activities contribute to evolution research, phage application, phage genomics and taxonomy (ICTV). In particular, phages against the ESKAPE pathogens came into our focus and intensified phage genomics which represents the state-of-the-art methodology at the DSMZ that can be used to shed light on the rich unknown genetic potential of the phage biodiversity. Additionally, a young specific phage collection is the Therapeutic Phage Bank established as an open collection under the MoU with P.H.A.G.E.: phages bearing a therapy potential for human medical use can be deposited without costs, a special MTA restricts direct therapeutic application. In our Phage Trapper project different and special habitats are explored to find new phages for collection and research activities on diverse topics, both must go hand-in-hand. All phages are welcome at the DSMZ, we like to share with you the phage bioresources, data and expertise!






Reference:
Posters Day 2-T03-Pos-04
Session:
Posters Covering Ecology, Host population control, Co-Evolutionary dynamics and Subversion/Evasion of Host Defences
Presenters:
Johannes Wittmann
Session:
Day 2 Posters Covering: Ecology, Host population control, Co-evolutionary dynamics and Subversion/Evasion of host defences
Presentation type:
Poster presentation
Room:
Poster Halls
Date:
Tuesday, 19 July 2016
Time:
12:05 - 15:00