School of Medicine - Year 1 MBChB Curriculum

Lecture 7: "How do we stomach our food?"

1. gastric motility in response to a meal
2. the cellular origin, composition and function of gastric juice
3. Cellular mechanisms of gastric secretion (e.g. acid from gastric parietal cells, role of the proton pump)
4. the regulation (and phases) of gastric acid secretion in response to ingestion of a meal
5. how we can control excess acid secretion
6. the role of the Helicobacter pylori in gastric disease.

Useful links

• Gastrointestinal Physiology text
   
  
• Parietal cell - gastric acid secretion animation
   
  
• Physiology of Acid secretion
   
  
• Drugs used in acid suppression
   
  
• Proton pump inhibitor Omeprazole - mode of action
   
  
• H.pylori and carcinogenic risk to humans
   
  
• Nobel prize for medicine 2005 - H. pylori. Contents include….discovery, mechanisms of infection and inflammation.