Dr Faviel Gonzalez
Post-Doctoral Research Associate
Tel: +44 (0) 151 795 4555
Affiliations
- Member of the Post-genomic Bioinformatics Group, University of Liverpool.
- Member of the European Network of the HLA diversity for histocompatibility, clinical transplantation, epidemiology and population genetics.
Research Interests
Bioinformatics, Proteomics, Immunogenetics, Population Genetics.
Current project
My research is focussed on the development of an open-source software workbench for the analysis of quantitative proteomics data. The software includes the integration of methods, definition of standards for data exchange and development of an environment for the submission and analysis of proteomics datasets.
- http://www.proteosuite.org
Open-source software for the analysis of quantitative proteomics data.
Other projects
I have also participated in the development of bioinformatics web-based tools for the analysis of several immune genes. Some of the developments include the construction of a website for the analysis of allele, haplotype and genotype frequencies in different human populations. As part of data standardisation, I am also interested on data exchange protocols. At present, I am on charge of the development and maintenance of the www.allelefrequencies.net website.
- http://www.allelefrequencies.net
Public database for the storage of allele frequencies from different polymorphic regions in the human genome.
Publications
2012
- Gonzalez-Galarza FF , Lawless C, Hubbard S, Hermjakob H and Jones AR. A critical appraisal of techniques, software packages and standards for quantitative proteomic analysis OMICS 2012 (Submitted for publication).
- Sanchez-Mazas A, Vidan-Jeras B, Nunes JM, Fischer G, Little AM, Bekmane U, Buhler S, Buus S, Claas F, Dormoy A, Dubois V, Eberhard HP, Eglite E, Gonzalez-Galarza F , Grubic Z, Ivanova M, Lie B, Ligeiro D, Lokki ML, Maldonado-Torres H, Marsh SGE, Martins da Silva B, Martorell J, Mendonça D, Middleton D, Muller C, Papasteriades C, Poli F, Riccio ME, Spyropoulou Vlachou M, Sulcebe C, Tonks S, Toungouz-Nevessignsky M, Vangenot C, van Walraven AM and Tiercy JM. Strategies to work with HLA data in human populations for histocompatibility, clinical transplantation, epidemiology and population genetics: HLA-NET methodological recommendations International Journal of Immunogenetics 2012 (In press).
- Alfirevic A, Gonzalez-Galarza F , Bell C, Martinsson K, Platt V, Bretland G, Evely J, Lichtenfels M, Cederbrant K, French N, Nasibitt D, Park K, Jones AR, Pirmohamed M. In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers Genome Medicine 2012 (In press).
2011
- Gonzalez-Galarza FF, Christmas S, Middleton D and Jones AR. Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations Nucleic Acid Research 2011 39:D913-D919. [Full Text - Free Access] (Featured article)
2010
- Middleton D, Gonzalez F. Immunogenetic Databases. In: Mehra N, eds. The HLA complex in Biology and Medicine: A resource book. New Delhi: Jaypee 2010, 119-134.
- Middleton D, Gonzalez-Galarza F, Meenagh A, Gourraud PA. Diversity of KIR genes, alleles and haplotypes In: J. Zimmer eds. Natural Killer Cells: At the Forefront of Modern Immunology. Berlin: Springer-Verlag 2010; 63-91.
2009
- Middleton D, Gonzalez F. The extensive polymorphism of KIR genes. Immunology 2009 129:8-19. [Abstract]
- Middleton D, Gonzalez F, Fernandez-Vina M, et al. A bioinformatic approach to ascertaining the rarity of HLA alleles. Tissue antigens 2009 74:480-485. [Abstract]