School of Medicine - Year 1 MBChB Curriculum

GASTROINTESTINAL SYSTEM LECTURE BLOCK        Professor Barry Campbell

Lecture 11 - "Gut fluid balance - Intestinal Secretion & Absorption"       


Objective: - To develop an understanding of:
  1. secretion and absorption of water along the GI tract
  2. role of the small and large bowel in maintaining fluid balance
  3. factors which influence absorption and secretion in the intestine to maintain overall daily gut fluid balance
  4. the molecular and cellular mechanisms of enterocyte membrane transport of water and electrolytes
  5. factors leading to malabsorption of water and electrolytes resulting in diarrhoea (excessive loss of water in the faeces)
  6. why ingestion of glucose-electrolyte solution (Oral rehydration therapy) has proven to be such an effective therapeutic means of reducing fluid loss in patients with diarrhoea (e.g. Cholera)
Lecture handout (PDF format)             Powerpoint presentation (PDF format)

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