School of Dentistry - Year 1 BDS Curriculum

Plenary: "Protection of the Digestive system"

1. the defensive role of the mucosal barrier and the consequences for the gut when protection fails
2. how the gastrointestinal epithelium responds when insult leads to injury
3. how the gut detects and removes infectious agents
4. the mechanisms to sense and remove any damaged/mutated cells
5. the mechanisms and regulation of vomiting

Useful links

• The gastrointestinal barrier
   
  
• Dignass AU (2001). Mechanisms and modulation of intestinal epithelial repair. Inflamm. Bowel Dis., 7(1): 68-77
   
  
• Wallace JL, Granger DN (1996). The cellular and molecular basis of gastric mucosal defense. FASEB J. 1996 May;10(7):731-40
   
  
• GH Carpenter (2013). The Secretion, Components, and Properties of Saliva. Annual Review of Food Science and Technology 4:267-276
   
  
• The immune system
   
  
• apoptosis
   
  
• Physiology of vomiting