School of Medicine - Year 1 MBChB Curriculum

Lecture 15: "Gut communication with its environment - Nutrient sensing & uptake"

1. Nutrient sensing in the GI tract and the “Gustotopic” map of the tongue
2. Taste receptors including the different types and taste modalities
3. Taste receptors in the gut (stomach, gallbladder, small intestine, colon) and relevant nutrient transport mechanisms
4. Nutrient sensing and the potential for future medicines

Useful links

• Lets talk about taste
   
  
• Receptors and cells for mammalian taste - Chandrashekar et al. Nature 2006, 444; 288-94
   
  
• Neural Pathways of Smell, Taste, and Touch
   
  
• Taste: The tongue
   
  
• The Bittersweet Truth of Sweet and Bitter Taste Receptors
   
  
• Hormones of the gut