University of Liverpool

Ageing Research

I am a third year PhD student in the Integrative Genomics of Ageing Group at the University of Liverpool, United Kingdom. My research is directed towards the potential roles of Adenosine to Inosine RNA editing in mammalian ageing, a process that has previously been linked to various neurodegenerative diseases.

“Nothing in biology makes sense except in the light of evolution”

Theodosius Dobzhansky (1900 – 1975)

It is obvious when comparing different species that their lifespans have been manipulated by natural selection. Therefore I am also interested in understanding the difference between closely related long-lived and short-lived species. In particular, I have been involved in the genomic sequencing of the naked mole-rat, in addition to gene expression studies.

“The idea is to die young as late as possible”

Ashley Montagu (1905 – 1999)

It is a common misconception that ageing research will only extend the length of time that a person is frail and senile. The ultimate goal of my present and future research is to help understand ageing and eventually to lead to treatments that will extend the healthspan of people.

Centenarians

Since 2008 I have been working with the Gerontology Research Group as a British correspondent to validate the lifespans of the oldest people in the world. During this time I have also been compiling a list of the oldest people in the United Kingdom. This has given me a great insight into the demographics of the oldest old. My work in identifying a First World War veteran was also mentioned in several national news media, including the BBC and Daily Telegraph.

“Remember that life's length is not measured by its hours and days, but by that which we have done therein”

Walter Breuning (1896 – 2011)

Finally, my own ultimate goal is not necessarily to live as long as possible, but to live a long, healthy, successful life.